Nintoin 50mg Capsule (Nitrofurantoin) is a bactericidal antibiotic which helps to treat or prevent urinary tract infections. It should be used with caution in patients with kidney disease.
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Nintoin 50mg Capsule contains Nitrofurantoin, which is an antibiotic used to treat and prevent urinary tract infections (UTIs). UTIs can occur in various parts of the urinary system, including the bladder, kidneys, ureters, and urethra. Common symptoms of UTIs include a strong urge to urinate, a burning sensation while urinating, decreased urine flow, cloudy urine, blood in urine, and pelvic pain (more commonly in women).
Your doctor will monitor the functioning of your lungs and liver regularly while you are taking Nintoin 50mg Capsules. It is important to note that this medication may interfere with urine tests for sugar, potentially leading to a false positive result.
Caution should be exercised when taking Nintoin 50mg Capsule in patients with lung or liver disease, anemia, diabetes (high blood sugar), conditions causing severe weakness, electrolyte imbalance, vitamin B deficiency, and severe kidney disease.
The use of Nintoin 50mg Capsule is not recommended in pregnant women during labor or delivery due to potential harm to the baby. It should be used with caution in breastfeeding women.
This medication should be avoided in infants below 3 months of age and used with caution in elderly patients.
The most common side effects of Nintoin 50mg Capsule include nausea, vomiting, loss of appetite, and diarrhea. If any of these side effects worsen, it is important to consult your doctor.
It is advisable to consult with a healthcare professional for personalized guidance and to address any concerns regarding the use of Nintoin 50mg Capsule.
Avoid consumption of alcohol while taking Nintoin 50mg Capsule because it might make you dizzier.
Nintoin 50mg Capsule can be used during pregnancy only if prescribed by your doctor. It should, however, not be used at this stage of pregnancy (during labor or delivery) as it may harm the unborn baby. It is essential to always consult a doctor before starting any medicine during pregnancy.
As Nintoin 50mg Capsule is known to pass into breast milk, you should consult your doctor before using this medicine during breastfeeding.
Nintoin 50mg Capsule may cause dizziness and drowsiness, hence you need to be cautious while driving.
Nintoin 50mg Capsule is not recommended for use in patients with kidney disease that severely affects the function of the kidneys. It should be used with caution in patients with kidney problems. Consult your doctor before taking Nintoin 50mg Capsule.
Nintoin 50mg Capsule should be taken with caution in patients with liver disease. Consult your doctor before taking Nintoin 50mg Capsule.
Nintoin 50mg Capsule effectively treats and prevents urinary tract infections by killing bacteria present in the urethra, bladder, and/or kidneys. It mainly acts by disrupting the production of genetic material present in the bacterial cell.
Nintoin 50mg Capsule is an antibiotic medicine. It is used for the treatment and prevention of uncomplicated urinary tract infections.
Nitrofurantoin is an antibacterial agent that works particularly well for infections of the urinary tract. Extremely solvent in urination, nitrofurantoin may give poop a brown hue. Ribosomal proteins and other macromolecules produced by bacteria are inactivated or altered by nitrofurantoin. It has been demonstrated that nitrofurantoin is effective against pursuing microscopic organisms: Grass-Feeding Aerobes Enterococcus faecalis, Staphylococcus aureus, Streptococcus agalactiae, Gather D streptococci, and Viridans gather streptococci are among the staphylococci that are Coagulase-negative and include Staphylococcus epidermidis. Escherichia coli, Citrobacter amalonaticus, Citrobacter diversus, Citrobacter freundii, Klebsiella oxytoca, and Klebsiella ozaena are examples of Gram-negative Aerobes.
For adults, the recommended dosage of Nitrofurantoin capsules is as follows:
Take Nintoin 50mg Capsule as advised by your physician. Swallow Nintoin 50mg Capsule with a glass of water and do not crush or chew it. Nintoin 50mg Capsule should always be taken with food or milk for effective working and to avoid stomach upset. It's important to note that these dosage recommendations are general guidelines and may vary depending on individual factors and the specific instructions provided by your healthcare provider. Always follow your doctor's instructions regarding the dosage and duration of Nitrofurantoin treatment.
When Nitrofurantoin is taken together with antacids containing Magnesium Trisilicate, it can interfere with the absorption and effectiveness of certain uricosuric medicines, such as Probenecid and Sulfinpyrazone. Uricosuric medicines are used to treat conditions like gout by increasing the excretion of uric acid from the body.
The presence of Magnesium Trisilicate in antacids can reduce the absorption rate and extent of these uricosuric medicines, making them less effective in lowering uric acid levels. Additionally, Nitrofurantoin can also be affected by the interaction with Magnesium Trisilicate, as it can limit the secretion of Nitrofurantoin in the renal tubules (part of the kidney involved in urine formation and excretion).
To ensure the optimal effectiveness of both Nitrofurantoin and uricosuric medicines, it is advisable to separate their administration. It is recommended to take Nitrofurantoin and uricosuric medicines at different times, with an appropriate time interval between them. This helps to avoid any potential interactions and allows for proper absorption and effectiveness of each medication.
Severe Renal Impairment: If you have severe renal impairment, such as anuria (absence of urine production), oliguria (reduced urine production), significantly elevated serum creatinine levels, or creatinine clearance (CrCl) below 60 ml/min, the use of nitrofurantoin may be contraindicated or require dosage adjustment. Your healthcare provider will determine the appropriate course of action.
Hypersensitivity to Nitrofurans: If you have a known hypersensitivity or allergic reaction to nitrofurans or any components of nitrofurantoin, its use should be avoided. Allergic reactions can range from mild skin rashes to severe systemic reactions, including anaphylaxis.
G6PD Deficiency: Nitrofurantoin use should be avoided in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. G6PD deficiency is an enzyme deficiency that can lead to hemolysis (destruction of red blood cells) when exposed to certain medications, including nitrofurantoin.
Infants Under 3 Months of Age: Nitrofurantoin is not recommended for use in infants younger than 3 months old. Safety and efficacy data in this age group are limited.
Pregnancy at Term, During Labor and Delivery, or Imminent Onset of Labor: Nitrofurantoin should not be used in pregnant women at term (near the end of pregnancy), during labor and delivery, or when the onset of labor is imminent. There is a potential risk to the baby during these stages.
Pregnancy Category B. Limited and inconclusive studies have been conducted on the use of this medication in pregnant women. It should only be used during pregnancy if it is absolutely necessary. Small amounts of nitrofurantoin have been detected in human breast milk. Considering the potential for significant side effects in nursing infants under one month old, a decision should be made regarding whether to discontinue breastfeeding or discontinue the medication, taking into account the importance of the drug to the mother.
In elderly patients, caution should be exercised when using Nitrofurantoin. It is important to monitor hepatic (related to the liver) and pulmonary (related to the lungs) function during prolonged therapy to ensure the medication is well-tolerated and does not cause any adverse effects.
If a patient has pre-existing pulmonary, hepatic, neurological, or allergic disorders or a predisposition to peripheral neuropathy (damage to the nerves in the extremities), special care should be taken when considering the use of Nitrofurantoin. This includes individuals with conditions such as renal impairment (kidney dysfunction), anemia, diabetes mellitus (high blood sugar), electrolyte imbalance, debility (weakness), and vitamin B deficiency.
If signs of peripheral neuropathy, such as numbness, tingling, or pain in the hands or feet, occur during treatment with Nitrofurantoin, the medication should be discontinued.
Regarding lactation, Nitrofurantoin enters breast milk. Therefore, it is recommended to discontinue the drug or avoid nursing while taking Nitrofurantoin to prevent potentially adverse effects on the breastfed infant.
Do not store above 30°C. Keep away from light and out of the reach of children.
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